Speech difficulties in individuals with Autism Spectrum Disorder (ASD) can be complex, as they can be caused or exacerbated by a variety of underlying medical issues. Some of these factors might be related to neurological, physiological, or psychological aspects of a person's health. A thorough evaluation is necessary to identify the specific cause and develop appropriate interventions. Several contributing factors to speech issues in children with ASD include:

• Seizures
• Sleep apnea
• Cerebral Folate Deficiency
• Vitamin and/or Mineral Deficiencies:
  • Essential Fatty Acid (EFA) deficiency
  • B12 deficiency
  • Other vitamin and nutrient deficiencies, such as B6, 5MTHF, B1, creatine, L-Carnitine, CoQ10, sulfur-rich compounds, magnesium, iron, butyrate
• Tongue-tie
• Retained primitive reflexes
• Mitochondrial dysfunction